abstract：:Congestive heart failure (CHF) is the most common discharge diagnosis for elderly patients. The survival of elderly (age greater than or equal to 75 years) patients with CHF has not recently been reported, especially with reference to left ventricular ejection fraction (LVEF). A patient database was searched for the d...

journal_title：Age and ageing

authors： Taffet GE,Teasdale TA,Bleyer AJ,Kutka NJ,Luchi RJ

更新日期：1992-01-01 00:00:00

abstract：:We have measured the rate of induction of the microsomal monooxygenase enzyme aryl hydrocarbon hydroxylase (AHH) in isolated peripheral blood monocytes from young and elderly donors. There was no effect of age on rate of induction. The mechanisms underlying impaired induction of drug metabolism in elderly people remai...

journal_title：Age and ageing

authors： George G,Wynne H,Woodhouse K

更新日期：1991-11-01 00:00:00

abstract：:Cellular immune function declines with age and is implicated in the increased incidence of cancer, and morbidity and mortality associated with infections in elderly people. Elderly people are at risk of nutritional depletion, including of zinc, and zinc is known to influence immunity. The present study assessed zinc s...

journal_title：Age and ageing

authors： Goode HF,Penn ND,Kelleher J,Walker BE

更新日期：1991-09-01 00:00:00

abstract：:Visual acuity and contrast sensitivity were measured in 95 residents of a hostel for the aged (mean age = 83 years) using a dual-contrast letter chart and the Melbourne Edge Test (MET). Vision (as measured by visual acuity, the MET, low-contrast visual acuity, and difference between high- and low-contrast acuity) decr...

journal_title：Age and ageing

authors： Lord SR,Clark RD,Webster IW

更新日期：1991-05-01 00:00:00

abstract：:A random sample of 241 patients from General Practice registers in London were interviewed to assess alcohol consumption, cognitive impairment, depression and other factors. Fifty-one per cent of men and 22% of women reported use of alcohol in the previous 3 months. No significant association was found between reporte...

journal_title：Age and ageing

authors： Iliffe S,Haines A,Booroff A,Goldenberg E,Morgan P,Gallivan S

更新日期：1991-03-01 00:00:00

abstract：:Of 212 cases of peritonitis found in a retrospective study of geriatric inpatients, the most common causes were mesenteric infarction, malignancy, intestinal obstruction, perforated peptic ulcer, cholecystitis, diverticulitis and perforation of the urinary bladder. The diagnostic accuracy was 47%. Abdominal pain had b...

journal_title：Age and ageing

authors： Wroblewski M,Mikulowski P

更新日期：1991-03-01 00:00:00

abstract：:The effect of tamoxifen on the vaginal mucosa and on serum oestrone, oestradiol and gonadotrophin concentrations was investigated in a group of nine postmenopausal women with non-metastatic breast cancer. Compared with fit age-matched controls, the vaginal pH in the tamoxifen-treated group was significantly lower and ...

journal_title：Age and ageing

authors： Miodrag A,Ekelund P,Burton R,Castleden CM

更新日期：1991-01-01 00:00:00

abstract：:Forty patients over 65 years of age with fractures of the proximal femur, whose operation was delayed more than 24 hours after admission for medical reasons, were studied. Length of post-operative stay on the orthopaedic wards, mobility after one month and need for continuing supervision by the geriatric services, aft...

journal_title：Age and ageing

authors： Harries DJ,Eastwood H

更新日期：1991-01-01 00:00:00

abstract：:Four hundred and fifty patients aged 75 years or older were followed up after discharge from an accident and emergency department. Forty-three per cent of all patients experienced some loss of functional independence. A small number, 5.6%, were readmitted to hospital within 14 days. This group were significantly less ...

journal_title：Age and ageing

authors： Rowland K,Maitra AK,Richardson DA,Hudson K,Woodhouse KW

更新日期：1990-11-01 00:00:00

abstract：:Previous work has shown persistent elevations in plasma cortisol concentration following upper femur fracture in elderly people. To investigate this phenomenon further, we measured plasma cortisol and adrenocorticotrophin (ACTH) and performed overnight dexamethasone suppression tests in carefully characterized patient...

journal_title：Age and ageing

authors： Roberts NA,Barton RN,Horan MA,White A

更新日期：1990-09-01 00:00:00

abstract：:Drug compliance was assessed amongst all 91 patients attending a psychogeriatric day hospital during July 1988. Of the 86 patients taking medication, the 57 functionally and 29 organically ill patients were interviewed at home, the latter with their carers. A disparity in results was shown when compliance was measured...

journal_title：Age and ageing

authors： Rosenvinge HP,Groarke EP,Bradshaw JW

更新日期：1990-05-01 00:00:00

abstract：:A sample of 761 subjects 70 years and over was drawn from general-practice records of a rural township. Each subject was assessed and followed for 1 year to determine the incidence of and factors related to falls. The fall rate (number of falls per 100 person-years) increased from 47 for those aged 70-74 years to 121 ...

journal_title：Age and ageing

authors： Campbell AJ,Borrie MJ,Spears GF,Jackson SL,Brown JS,Fitzgerald JL

更新日期：1990-03-01 00:00:00

abstract：:The Rivermead ADL scale was developed for assessing activities of daily living in stroke patients but was not validated for elderly subjects. This study was designed to validate the scale for patients aged over 64 years. A series of 150 stroke patients was assessed on the scale, of whom 103 were aged over 64 years. Th...

journal_title：Age and ageing

authors： Lincoln NB,Edmans JA

更新日期：1990-01-01 00:00:00

abstract：:The results reported here are from a 2-year follow-up study of 58 elderly patients in a continuing-care unit. Most of these patients were in a hyperosmolar state at the time of entry (mean plasma osmolality 304 +/- 8 mOsmol/kg). The survival of those patients with the highest osmolality (greater than 308 mOsmol/kg) wa...

journal_title：Age and ageing

authors： O'Neill PA,Faragher EB,Davies I,Wears R,McLean KA,Fairweather DS

更新日期：1990-01-01 00:00:00

abstract：:Serological tests for syphilis were performed on 659 elderly patients admitted to hospital medical and psychiatric departments. Positive tests were found in 23 patients (3.5% of the sample), 17 women and 6 men. Six were subsequently discovered to have been treated previously for syphilis, and one other had radiologica...

journal_title：Age and ageing

authors： Corrado OJ,Bowie PC,Bagnall WE,Waugh MA

更新日期：1989-11-01 00:00:00

abstract：:A prospective study was carried out on 288 general surgical patients aged 65 years and over. Over 40% of patients suffered no post-operative complication. The commonest post-operative problem was respiratory, with 17% of patients having simple atelectasis, 12% acute bronchitis and 10% pneumonia. Six per cent of patien...

journal_title：Age and ageing

authors： Seymour DG,Vaz FG

更新日期：1989-09-01 00:00:00

abstract：:A 3-year prospective, controlled study of sports injuries in elderly athletes (over 60 years of age) treated at an outpatient sports clinic was carried out in order to determine the number, profile, and specific features of these injuries compared with those of young athletes (between 21 and 25 years). During the stud...

journal_title：Age and ageing

authors： Kannus P,Niittymäki S,Järvinen M,Lehto M

更新日期：1989-07-01 00:00:00

abstract：:The measurement of cutaneous pain threshold using the Neuromod Selectra Model 7750 Transcutaneous Neuronal Electrical Stimulator is described. Pain threshold, measured in 520 healthy volunteers aged 5-105 years, increased with age. Consistent values were obtained in 22 healthy volunteers on three successive days. Pain...

journal_title：Age and ageing

authors： Tucker MA,Andrew MF,Ogle SJ,Davison JG

更新日期：1989-07-01 00:00:00

abstract：:Twenty-four incontinent elderly institutionalized subjects with detrusor instability participated in a double-blind placebo-controlled trial of oxybutynin chloride. Patients were randomly assigned to oral oxybutynin 5 mg or placebo twice daily. Administration continued for 8 days; a 6-day washout period was followed b...

journal_title：Age and ageing

authors： Zorzitto ML,Holliday PJ,Jewett MA,Herschorn S,Fernie GR

更新日期：1989-05-01 00:00:00

abstract：:The change in mental and physical functioning over 5 years for 594 survivors of a community survey of the elderly is described. An increase in cognitive impairment, physical disability and incontinence over the period was found with increasing age. Women in the two oldest age groups had a significantly greater increas...

journal_title：Age and ageing

authors： Jagger C,Clarke M,Cook AJ

更新日期：1989-03-01 00:00:00

abstract：:Data on National Health Service (NHS) dental care utilization by the elderly are analysed to consider the distribution of dental care according to the charge status of the patient. Considerable and significant differences are observed in the type and amount of dental care provided to elderly patients exempt and not ex...

journal_title：Age and ageing

authors： Birch S

更新日期：1989-03-01 00:00:00

abstract：:The capacity of peripheral blood mononuclear cells (PBMC) isolated from patients with Alzheimer's disease to produce interleukin-1 and -2 (IL-1, IL-2) was compared to that of cells from age-matched controls and young healthy subjects. There was no difference in the production of both interleukins between patients and ...

journal_title：Age and ageing

authors： Bessler H,Sirota P,Hart J,Djaldetti M

更新日期：1989-01-01 00:00:00

abstract：:Interleukin-1 mediates the febrile response which is often said to be reduced in the elderly. Interleukin-1 production by monocytes cultured in vitro and stimulated with bacterial lipopolysaccharide was measured. Three groups of subjects were studied; 40 normal young, 33 well elderly and 40 elderly with a history of r...

journal_title：Age and ageing

authors： Rudd AG,Banerjee DK

更新日期：1989-01-01 00:00:00

abstract：:We evaluated the effect of impaired hearing and vision on balance in a sample of 977 elderly people residing in the community. Of the sample, 21% reported balance problems, 27% vision problems, and 30% hearing problems. The increased relative risk for balance problems was 1.7 for each 10-year age increment. Women were...

journal_title：Age and ageing

authors： Gerson LW,Jarjoura D,McCord G

更新日期：1989-01-01 00:00:00

abstract：:Of 1042 individuals aged 65 years and over who were successfully interviewed in a community survey of health and physical activity, 35% (n = 356) reported one or more falls in the preceding year. Although the overall ratio of female fallers to male fallers was 2.7:1, this ratio approached unity with advancing age. Mob...

journal_title：Age and ageing

authors： Blake AJ,Morgan K,Bendall MJ,Dallosso H,Ebrahim SB,Arie TH,Fentem PH,Bassey EJ

更新日期：1988-11-01 00:00:00

abstract：:One hundred and twenty-two consecutive patients admitted with acute stroke in a carotid distribution had venous blood taken for haematocrit (Hct), haemoglobin (Hb), white cell count (WCC) and urea estimations. Patients were followed for 12 weeks to determine the influence of haematocrit upon fatality. There were 96 pa...

journal_title：Age and ageing

authors： Gray CS,French JM,James OF,Bates D,Cartlidge NE

更新日期：1988-11-01 00:00:00

abstract：:A study of 414 elderly residents of sheltered accommodation in West Essex investigated the degree to which health, physical handicap and support from community care services affected dental needs and utilization of dental services. The study population had a mean age of 77 years, 77% lived alone, 17% were housebound a...

journal_title：Age and ageing

authors： Tobias B

更新日期：1988-03-01 00:00:00

abstract：:The contribution of the elderly to the workload of a combined consultative District Hospital Gastroenterology Clinic has been studied over a 12-year period. The elderly group comprise 24% of the total referrals with a gradually increasing trend over successive years. The service implications are discussed and the main...

journal_title：Age and ageing

authors： Purkayastha SK,Salter RH,Holmes KM

更新日期：1988-01-01 00:00:00

abstract：:The present study was undertaken to define the hormonal response to thyroid-releasing hormone (TRH) further in a large, healthy, ambulatory elderly group. Seventy-seven subjects over 60 years old, 30 males (MA) and 47 females (FA), and control subjects, 22 males (MC) and 42 females (FC) were studied. No difference in ...

journal_title：Age and ageing

authors： Kaiser FE

更新日期：1987-11-01 00:00:00

abstract：:Of 60 patients referred for geriatric assessment with clinically significant hypochromic anaemia, in the absence of frank bleeding, 44 underwent upper gastrointestinal and 27 lower gastrointestinal investigations. The probability of identifying a potential cause at upper gastrointestinal endoscopy was three times that...

journal_title：Age and ageing

authors： Calvey HD,Castleden CM

更新日期：1987-11-01 00:00:00

abstract：:The frequency of snoring was studied in 46 patients with Alzheimer's disease (AD), 37 with multiinfarct dementia (MID), and in a random sample of 124 elderly community residents without known diseases affecting higher cortical functions. The demented patients were reported to snore twice as frequently as the control s...

journal_title：Age and ageing

authors： Erkinjuntti T,Partinen M,Sulkava R,Palomaki H,Tilvis R

更新日期：1987-09-01 00:00:00

abstract：:Acute appendicitis in elderly patients has not been studied extensively in the United Kingdom. Studies were performed prior to the regular use of broad spectrum antibiotics and tended to include younger patients. We studied retrospectively all elderly patients (n = 30, mean age = 72 years) who presented in the years 1...

journal_title：Age and ageing

authors： McCallion J,Canning GP,Knight PV,McCallion JS

更新日期：1987-07-01 00:00:00

abstract：:We analysed 103 episodes of upper gastrointestinal bleeding in 88 elderly patients (age 76 +/- 7.7 years) to determine which of a group of 52 clinical and laboratory variables, measured on admission, best predicted continued or rebleeding, and death in these patients. Variables which related directly to the size of th...

journal_title：Age and ageing

authors： Booker JA,Johnston M,Booker CI,Tydd T,Mitchell R

更新日期：1987-07-01 00:00:00

abstract：:This paper describes how a sample of elderly people were identified from the electoral register using an initial postal screen, and reports a technique that was used to increase the response to the screen. ...

journal_title：Age and ageing

authors： Cartwright A,Smith C

更新日期：1987-03-01 00:00:00

abstract：:This paper discusses an assessment procedure for the formal identification of patients requiring long-stay geriatric care. It was introduced immediately prior to the reorganization of geriatric in-patient care at St Pancras Hospital which saw the abolition of mixed wards of acute, rehabilitation, and long-stay patient...

journal_title：Age and ageing

authors： Golding R,Lugon M,Hodkinson HM

更新日期：1987-01-01 00:00:00

abstract：:Previous studies have suggested that up to a fifth of people over the age of 80 years may suffer severe dementia-like illnesses. This total population survey of over a thousand people over the age of 75 suggests that the prevalence of marked cognitive impairment is much less than expected. However, differences in the ...

journal_title：Age and ageing

authors： Clarke M,Lowry R,Clarke S

更新日期：1986-09-01 00:00:00

abstract：:A total of 521 patients consecutively admitted to an acute geriatric unit were kept under surveillance by one observer during their stay. All drugs given to them and the occurrence of adverse events were recorded. One hundred and seventeen adverse drug reactions occurred in 94 patients representing 18.8% of the 500 pa...

journal_title：Age and ageing

authors： Leach S,Roy SS

更新日期：1986-07-01 00:00:00

abstract：:Ninety-nine residents, 10% of the total population of elderly in Part III accommodation in Newcastle upon Tyne, were examined for the presence of psychiatric disorder, tested for cognitive impairment, and rated for the presence of confusion. Those allocated a diagnosis of dementia were most impaired and confused, and ...

journal_title：Age and ageing

authors： Vardon VM,Blessed G

更新日期：1986-05-01 00:00:00

abstract：:Fifty-eight elderly hospital patients walked along a 10-m length of carpeted corridor and a 10-m length of vinyl-tiled corridor. Gait speed and step length were significantly greater on the carpeted than on the vinyl surface. ...

journal_title：Age and ageing

authors： Willmott M

更新日期：1986-03-01 00:00:00

abstract：:Faecal incontinence occurring at least once weekly was found in 10.3% of residents in 30 residential homes for the elderly. Fifty-two randomly-selected incontinent residents were prescribed treatment and the outcome was compared with 30 incontinent residents acting as controls. The vast majority of all incontinent res...

journal_title：Age and ageing

authors： Tobin GW,Brocklehurst JC

更新日期：1986-01-01 00:00:00